Searchable abstracts of presentations at key conferences on calcified tissues

ba0001w5.2 | Anabolic bone therapies | ECTS2013

Wnt signalling in and out of bone

Krishnan Venkatesh

The Wnt pathway engages both canonical and non-canonical signalling to accomplish a salutary benefit of increased bone mass, as evidenced by the presence of individuals with high bone mass, who exhibit specific functional variants in members of the pathway. This talk will highlight the importance of the influence on Wnt signalling being received by the bone in response to loading and the signals emanating from bone that influence overall metabolism and health in the whole anim...